
Injecting PDLLA Collagen Biostimulator, in Bangkok
”We, Mingkwan Clinic in Bangkok, are pleased to introduce PDLLA, a collagen biostimulator, which offers an innovative option for skin rejuvenation. PDLLA is a collagen stimulant used worldwide, with over one million bottles sold. It is used for skin rejuvenation, reducing wrinkles, tightening the skin, minimizing pores, improving acne scars, and providing a hydrated, healthy glow. It is approved by the Thai FDA as an injectable medical device.
Contents – Click to Read
- What is PDLLA?
- What are its ingredients?
- How does PDLLA work?
- Is PDLLA a filler?
- How is PDLLA different from other collagen biostimulators?
- What are the benefits of PDLLA?
- Who is it suitable for?
- Where can it be injected?
- How soon will I see results?
- How often should PDLLA be injected?
- How long do PDLLA results last?
- Is PDLLA safe?
- Can it be dissolved?
- What is the treatment process?
- Is PDLLA injection painful?
- What are the side effects?
- Will it cause swelling?
- Can PDLLA be combined with other treatments?
- Who should not use PDLLA?
- Can it be injected in older individuals?
- Can PDLLA (Biostimulator) treat acne scars?
- Pre-treatment guidelines
- Post-treatment care
- Cost of PDLLA
- How to verify authentic PDLLA?
What is PDLLA?
- PDLLA is a collagen biostimulator designed to rejuvenate skin. Once injected, it acts as a temporary scaffold that stimulates collagen production and gradually dissolves without leaving residue.
- PDLLA is specifically formulated for shallow injections (subdermis) for “glass skin” effects, making it suitable for areas like under the eyes.
What are its ingredients?
The vial contains two main ingredients: PDLLA (Poly D-L-Lactic Acid), a natural polymer that stimulates collagen production, reducing wrinkles, improving scars, and tightening skin; and Non-Cross-Linked Hyaluronic Acid, which hydrates and plumps the skin, giving it a glowing appearance.

How does PDLLA work?
- Injecting PDLLA into the dermal layer will acts as a tissue stimulant. This triggers a natural healing response, encouraging collagen and elastin production. The result is self-repairing, natural-looking skin improvements that last.
- The other ingredient, Non-Cross-Linked Hyaluronic Acid, is a liquid HA that does not form lumps. When injected, it helps hydrate and plump the skin for a dewy glow.
Is PDLLA a filler?
No, PDLLA is not a filler or volumizer. It is a collagen biostimulator that promotes the skin’s natural collagen and elastin production, helping the skin repair itself naturally.
How is PDLLA different from other collagen biostimulators?
- PDLLA is spherical, bubble-like structure minimizes tissue damage and reduces the risk of lumps, making it safe for delicate areas like under the eyes.
- Unlike others that target deeper layers, PDLLA is specifically designed for shallow dermal injections to enhance skin quality.
- The product includes hyaluronic acid for immediate skin hydration, unlike other biostimulators that require waiting for collagen production.

What are the benefits of PDLLA?
PDLLA stimulates collagen and elastin production, hydrates the skin, and provides the following benefits:- Prevents premature wrinkles and softens existing ones.
- Firms and tightens the skin.
- Reduces pore size and smoothens skin texture.
- Repairs scars, acne marks, and stretch marks.
- Hydrates and gives a radiant glow to the skin.

Who is it suitable for?
- Individuals looking for skin maintenance and future problem prevention.
- Those with fine lines around the eyes and neck.
- People with loose or sagging skin.
- Those with scars, acne marks, or stretch marks.
- Individuals with large pores and rough skin.
- People with dry, dehydrated skin.
Where can it be injected?
PDLLA can be injected into any area that needs collagen stimulation, including the face, neck, hands, thighs, and abdomen.
How soon will I see results?
- Immediately after injection, some areas may appear fuller due to the PDLLA solution.
- Collagen production begins after two weeks, with noticeable skin firmness and smoothness in about six weeks.
How often should PDLLA be injected?
It is recommended to inject PDLLA monthly for three consecutive months and then every 6–12 months for maintenance.

How long do PDLLA results last?
After completing the recommended protocol, PDLLA results can last up to two years, depending on skin care and maintenance.
Is PDLLA safe?
- PDLLA is made from natural polymers compatible with the human body.
- It dissolves naturally without leaving residues.
- PDLLA is GMO-free.
- Approved by Thai, Korean, and European FDA.
- Over one million bottles have been used worldwide.
Can it be dissolved?
- PDLLA acts as a scaffold for collagen production and dissolves naturally within six months.
- Unlike other biostimulators, PDLLA can be broken down using heat-based devices if lumps or nodules occur.
What is the treatment process?
- Cleanse the skin and apply numbing cream for 45 minutes, then remove the cream.
- The doctor uses a small needle for injections, taking 10–15 minutes.
Is PDLLA injection painful?
- With numbing cream and a small needle, the procedure causes minimal discomfort.
- PDLLA is less painful compared to Polynucleotide treatments.
What are the side effects?
Common side effects include small bumps, needle marks, bruising, or redness, which are temporary and resolve on their own.
Will it cause swelling?
- Small bumps from the injection typically disappear within 2–4 hours.
- Swelling subsides within 1–3 days.
Can PDLLA be combined with other treatments?
PDLLA can be safely combined with other treatments, but always consult your doctor beforehand.
Who should not use PDLLA?
- Pregnant or breastfeeding women.
- Those allergic to hyaluronic or polylactic acids.
- Individuals with autoimmune diseases.
- Anyone with wounds or inflammation at the injection site.
Can it be injected in older individuals?
Yes, PDLLA is suitable for all ages, improving skin health, elasticity, and hydration.
Can PDLLA (Biostimulator) treat acne scars?
- Yes, PDLLA stimulates collagen and elastin production to improve acne scars and can be used alone or with other treatments.
- PDLLA and hyaluronic acid work together to repair and hydrate the skin, enhancing the scar-healing process.
Pre-treatment guidelines
- Choose a clinic that sources PDLLA directly from authorized distributors.
- Inform your doctor about allergies, medications, medical history, and pregnancy status.
- Avoid certain vitamins and supplements like fish oil or ginkgo biloba at least one week before treatment to minimize bruising.
- Complete other facial treatments, such as lasers or HIFU, before the PDLLA injection.
Post-treatment care
- Small bumps at injection sites are normal and will subside within 2–4 hours.
- Swelling or redness will reduce within 1–3 days.
- Needle marks or mild bruising may fade within 7–14 days. Topical bruise-reducing creams or concealers can be used.
- Avoid makeup for the first 24 hours; if necessary, wait 4–6 hours.
- Use moisturizer and sunscreen to maintain skin health.
- Follow your doctor’s recommended treatment plan for the best results.
Cost of PDLLA
- 1 cc – 3,500 Baht
- 2 cc – 5,900 Baht
- 6 cc (1 bottle) – 14,900 Baht
How to verify authentic PDLLA?
- Scan the QR code on the product to check its details and clinic name.
- Avoid unverified products to prevent adverse effects.
Verify clinic names at >>> PDLLA Global website.